Flight Time from Iowa City to St. Louis
The flight from Iowa City to St. Louis covers about 221 mi and takes roughly 54 min nonstop. Flight duration estimate and fare guide.
Iowa City and St. Louis are about 221 mi (356 km) apart in a straight line. By road that works out to roughly 270 mi (434 km), a drive of about 4 hr 49 min. A nonstop flight covers the great-circle distance in approximately 54 min.
| Straight-line distance | 221 mi / 356 km |
| Road distance (est.) | 270 mi / 434 km |
| Driving time (est.) | 4 hr 49 min |
| Nonstop flight (est.) | 54 min |
| Driving fuel (est., 1-way) | $34 |
| Typical flight fare | $80–$250 |
| Geographic midpoint | 40.146, -90.849 |
How these estimates work
Straight-line distance uses the haversine formula on each city's coordinates. Road distance applies a circuity factor (~1.2–1.4×) and driving time a blended average speed. Flight time uses typical jet cruise speed plus ~30 minutes for taxi, climb and descent. Treat all figures as planning estimates.
Frequently asked questions
Iowa City to St. Louis is about 221 mi (356 km) in a straight line, and roughly 270 mi (434 km) by road.