Chicago to St. Louis is a 300-mile drive straight south on I-55 through the Illinois prairie — flat, fast, and largely featureless until the Mississippi River valley opens up approaching St. Louis.
Springfield, Illinois (Abraham Lincoln's hometown and the state capital) makes the only worthwhile cultural stop on this otherwise utilitarian stretch of interstate.
Stops Along the Way
Abraham Lincoln's hometown — the Lincoln Presidential Library and Museum is exceptional, and Lincoln's home and law offices are compelling historic sites.
Tips for This Trip
Springfield is a genuine stop, not just a gas break
The Abraham Lincoln Presidential Library and Museum is one of the best presidential libraries in the US.
St. Louis parking is abundant and cheap
Unlike Chicago, parking in downtown St. Louis and near the Gateway Arch is easy and affordable.
The Gateway Arch is best at sunset
The Arch's stainless steel catches extraordinary light at golden hour. Time your arrival for late afternoon.
🏨 Hotels in St. Louis
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Frequently Asked Questions
St. Louis is about 260 miles (418 km) from Chicago in a straight line, and approximately 300 miles (483 km) by road via Interstate 55 south through the Illinois prairie.